2,2-Diphenylacetyl chloride → (5-Diphenylacetylamino-tetrazol-2-yl)-acetic Acid Methyl Ester

HRID 2184982Notes

Reaction equation

HRID 2184982 reaction equation
[CH3:1][O:2][C:3](=[O:11])[CH2:4][N:5]1[N:9]=[N:8][C:7]([NH2:10])=[N:6]1.[C:12]1([CH:18]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:19](Cl)=[O:20])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH3:1][O:2][C:3](=[O:11])[CH2:4][N:5]1[N:9]=[N:8][C:7]([NH:10][C:19](=[O:20])[CH:18]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[N:6]1

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 42643124methyl 2-(5-amino-2H-1,2,3,4-tetrazol-2-yl)acetate

Product 1

HCID 10132626(5-Diphenylacetylamino-tetrazol-2-yl)-acetic Acid Methyl Ester

Procedure

The title compound, white solid, m.p. 168-169° and MS: (neg. ions): m/e=350.2 (M+−H) was prepared in accordance with the general method of example 1 from (5-amino-tetrazol-2-yl)-acetic acid methyl ester and diphenylacetyl chloride.

Sources & evidence

ORD record
ord-79d1c574d4ec4e6bb704289bdec4bb4b
Source dataset
uspto-grants-2002_06
Patent number
US06399641B1

Reaction notes

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