Thionyl Chloride → HCID 15895595, compound

Participants

Reaction Conditions

Reaction Steps

42 g (354 mmol) of thionyl chloride were added dropwise at 30° C. to a suspension of 42.8 g (177 mmol) of 4-(3-phenylureido)benzyl alcohol in 500 ml of dichloromethane. The mixture was subsequently stirred at 40° C. for 1 hour. After completion of the evolution of gas, the mixture was allowed to cool to room temperature. The precipitated product was filtered off with suction and washed with dichloromethane. Yield: 44.26 g (96%).

Provenance & Evidence