反应详情

Methyl 4-methoxyindoline-2(R/S)-carboxylate (0.89 g, 4.3 mmol) was dissolved in butylamine (40 ml) under nitrogen and the solution was then stirred at reflux for three hours. After cooling the mixture, the remaining butylamine was removed under vacuum. The crude product was recrystallized from diethyl ether in order to give an off-white solid.

1. temperatureat reflux for three hours
2. temperatureAfter cooling the mixture
3. customthe remaining butylamine was removed under vacuum
4. customThe crude product was recrystallized from diethyl ether in order
5. customto give an off-white solid