(Chloromethyl)cyclopropane → HCID 12971769, compound

HRID 2185790Notes

Reaction equation

HRID 2185790 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[CH:12]=[C:13]([C:18]([O:20][CH3:21])=[O:19])[C:14](=[O:17])[NH:15][N:16]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].Cl[CH2:23][CH:24]1[CH2:26][CH2:25]1>>[CH:24]1([CH2:23][N:15]2[C:14](=[O:17])[C:13]([C:18]([O:20][CH3:21])=[O:19])=[CH:12][C:11]([C:5]3[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=3)=[N:16]2)[CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 80013(Chloromethyl)cyclopropaneHCID 22452294HCID 22452294, compound

Product 1

HCID 12971769HCID 12971769, compoundYield 78.7%

Procedure

Using 6-(3,4-dimethoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and (chloromethyl)cyclopropane as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 78.7%.

Sources & evidence

ORD record
ord-3ed8940042f54dd3a6d5dd44376c06ad
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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