(Chloromethyl)cyclopropane → HCID 12971770, compound

HRID 2185791Notes

Reaction equation

HRID 2185791 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:11]=[C:12]([C:17]([O:19][CH3:20])=[O:18])[C:13](=[O:16])[NH:14][N:15]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].Cl[CH2:22][CH:23]1[CH2:25][CH2:24]1>>[CH:23]1([CH2:22][N:14]2[C:13](=[O:16])[C:12]([C:17]([O:19][CH3:20])=[O:18])=[CH:11][C:10]([C:4]3[CH:5]=[CH:6][C:7]([O:8][CH3:9])=[C:2]([F:1])[CH:3]=3)=[N:15]2)[CH2:25][CH2:24]1

Participants

3

Reactant 2

HCID 80013(Chloromethyl)cyclopropaneHCID 219914326-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one

Product 1

HCID 12971770HCID 12971770, compoundYield 54.7%

Procedure

Using 6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and (chloromethyl)cyclopropane as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 54.7%.

Sources & evidence

ORD record
ord-4d0f565f976f44a4a2f18a1c116c701e
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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