(Chloromethyl)cyclopropane → HCID 22452210, compound

HRID 2185792Notes

Reaction equation

HRID 2185792 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:11]=[C:12]([C:17]([O:19][CH3:20])=[O:18])[C:13](=[O:16])[NH:14][N:15]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].Cl[CH2:22][CH:23]1[CH2:25][CH2:24]1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:11]=[C:12]([C:17]([O:19][CH3:20])=[O:18])[C:13](=[O:16])[N:14]([CH2:22][CH:23]3[CH2:25][CH2:24]3)[N:15]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9]

Participants

3

Reactant 2

HCID 80013(Chloromethyl)cyclopropaneHCID 22452271HCID 22452271, compound

Product 1

HCID 22452210HCID 22452210, compoundYield 72.7%

Procedure

Using 6-(3-chloro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and (chloromethyl)cyclopropane as starting materials, the procedure of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 72.7%.

Sources & evidence

ORD record
ord-e1bc9fd0666143eab6177ec8f3ed0a00
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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