Benzyl Bromide → 2-Benzyl-4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one

HRID 2185796Notes

Reaction equation

HRID 2185796 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7](=[O:20])[NH:8][N:9]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH:11]=1)=[O:5])[CH3:2].[CH2:21](Br)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:21]([N:8]1[C:7](=[O:20])[C:6]([C:4]([O:3][CH2:1][CH3:2])=[O:5])=[CH:11][C:10]([C:12]2[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=2)=[N:9]1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 22452278HCID 22452278, compound

Product 1

HCID 224522592-Benzyl-4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-oneYield 75.3%

Procedure

Using 4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one and benzyl bromide as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 75.3%.

Sources & evidence

ORD record
ord-285874b7ab774513947c3e7717e7c793
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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