HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → 4-Benzylcarbamoyl-2-cyclopentylmethyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | HCID 22452171 | HCID 22452171 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 4-Benzylcarbamoyl-2-cyclopentylmethyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 22452296 | 78.5% |
Reaction Steps
In xylene, 2-cyclopentylmethyl-4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one and benzylamine were reacted at 140° C. for 2 hours. Post-treatments were conducted as in Example 68, whereby the title compound was obtained in a yield of 78.5%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06403586B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-53bdea1f92ef495b9fae36490d22d3e6 |
| Source note | uspto-grants-2002_06 |