Benzylamine → HCID 22452223, compound

HRID 2185816Notes

Reaction equation

HRID 2185816 reaction equation
C(O[C:4]([C:6]1[C:7](=[O:21])[N:8]([CH3:20])[N:9]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH:11]=1)=[O:5])C.[CH2:22]([NH2:29])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>C1(C)C(C)=CC=CC=1>[CH2:22]([NH:29][C:4]([C:6]1[C:7](=[O:21])[N:8]([CH3:20])[N:9]=[C:10]([C:12]2[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=2)[CH:11]=1)=[O:5])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 22452205HCID 22452205, compound

Product 1

HCID 22452223HCID 22452223, compoundYield 94.2%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

In xylene, 4-ethoxycarbonyl-6-(4-methoxyphenyl)-2-methyl-2H-pyridazin-3-one and benzylamine were reacted at 140° C. for 1 hour. Post-treatments were conducted as in Example 68, whereby the title compound was obtained in a yield of 94.2%.

Sources & evidence

ORD record
ord-9460f9dd0caf4be5ad227abba7f765d9
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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