反应详情

Ethyl iodide (1.1 g, 7.2 mmol) was added to an acetonitrile solution (40 ml) of 1,1,2-trimethylbenz[e]indole (1) (1.0 g, 4.8 mmol, Daiichi Pure Chemicals Co., Ltd.), and then the mixture was heated under reflux for 2 days. The reaction mixture was concentrated under reduced pressure, and ether (80 ml) was added to the residue. The resulting solid was repeatedly washed with ether to obtain the title compound (2) as a dark violet solid (1.6 g, 91%). mp. 213-218° C. (decomposition).

1. temperaturethe mixture was heated
2. temperatureunder reflux for 2 days
3. concentrationThe reaction mixture was concentrated under reduced pressure, and ether (80 ml)
4. additionwas added to the residue
5. washThe resulting solid was repeatedly washed with ether