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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2186140Generated: October 30, 2026

HCID 54450914, compound → HCID 54029713, compound

https://huagongshe.com/reaction/2186140

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54450914HCID 54450914—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 54029713HCID 5402971384.3%

Reaction Steps

A solution of 1-(1-acetyl-4-methoxycarbonylpiperidin-4-ylmethyl)-4-benzyloxycarbonyl-2-oxo-1,2,3,4-tetrahydropyrazine (2.4 g) and 10% palladium on carbon (500 mg) in methanol (100 ml) was stirred at room temperature for 15 hours, under hydrogen atmosphere, and the catalyst was filtered off. The reaction solution was concentrated to give colorless oil of the title compound (1.40 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06403595B1
Source datasetuspto-grants-2002_06
ORD IDord-7f09fce0d1734a029d1b0e0b516a1611
Source noteuspto-grants-2002_06