Methanol → Sbb056554

HRID 2186328Notes

Reaction equation

HRID 2186328 reaction equation
[C:1]([OH:12])(=[O:11])[CH2:2][O:3][CH2:4][CH2:5][O:6][CH2:7][C:8]([OH:10])=O.[C:13](=O)(O)[O-].[Na+].[CH3:18][OH:19]>>[CH3:18][O:19][C:8](=[O:10])[CH2:7][O:6][CH2:5][CH2:4][O:3][CH2:2][C:1]([O:12][CH3:13])=[O:11]

Participants

4

Reactant 3

HCID 887MethanolHCID 900393,6-Dioxaoctandioic acidHCID 516892Sodium Bicarbonate

Product 1

HCID 4534693Sbb056554

Procedure

Esterification of the crude 3,6-dioxaoctanedioic acid was accomplished as follows: To the reaction flask containing 36 g of the crude diacid, was added 110 ml of. methanol. This was stirred for 3 days at room temperature after which 15 g of sodium bicarbonate was added and stirred overnight. The mixture was filtered to remove solids. To the liquor was added an additional 10 g of sodium bicarbonate; this mixture was stirred overnight. The mixture was again filtered; the liquor was fractionally distilled.

Workup

  1. additionwas added 110 ml of
  2. additionwas added
  3. filtrationThe mixture was filtered
  4. customto remove solids
  5. additionTo the liquor was added an additional 10 g of sodium bicarbonate
  6. stirringthis mixture was stirred overnight
  7. filtrationThe mixture was again filtered
  8. distillationthe liquor was fractionally distilled

Sources & evidence

ORD record
ord-00f28fffdc7744d8b15d2a974bed5a86
Source dataset
uspto-grants-2002_06
Patent number
US06403655B1

Reaction notes

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