反应详情

5.11 cm3 of thionyl chloride were added dropwise, with stirring and under an inert atmosphere, at a temperature in the region of 20° C. to a solution of 1.74 g of 2-hydroxyethyl cycloheptyl sulfide in 30 cm3 of chloroform. After the addition, the reaction mixture was first stirred for 15 minutes at the same temperature and then for 1 hour at a temperature in the region of 600° C. The mixture was evaporated to dryness under reduced pressure (5 kPa) at a temperature in the region of 40° C., then the residue obtained was taken up with 2 times 50 cm3 of water and then 1 times 50 cm3 of a saturated sodium hydrogencarbonate solution. The ethereal solution, separated by settling, was dried over magnesium sulfate, filtered, and then concentrated under reduced pressure (5 kPa) at a temperature in the region of 400° C. 1.89 g of 2-chloroethyl cycloheptyl sulfide were obtained in the form of an oil.

1. additionAfter the addition
2. waitfor 1 hour at a temperature in the region of 600° C
3. customThe mixture was evaporated to dryness under reduced pressure (5 kPa) at a temperature in the region of 40° C.
4. customthe residue obtained
5. customThe ethereal solution, separated
6. dry with materialwas dried over magnesium sulfate
7. filtrationfiltered
8. concentrationconcentrated under reduced pressure (5 kPa) at a temperature in the region of 400° C