Hydrochloric Acid → HCID 70178378, compound

HRID 2186426Notes

Reaction equation

HRID 2186426 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:8]=[CH:9][N:10]([C@H:12]([CH3:31])[CH2:13][CH2:14][N:15](C(OC(C)(C)C)=O)[NH:16]C(OC(C)(C)C)=O)[CH:11]=2)[CH:2]=1.Cl>CO>[NH:15]([CH2:14][CH2:13][C@H:12]([N:10]1[CH:11]=[C:7]([C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)[N:8]=[CH:9]1)[CH3:31])[NH2:16]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 70178680HCID 70178680, compound

Product 1

HCID 70178378HCID 70178378, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
50 °C

Procedure

To a solution of bis(1,1-dimethylethyl) 1-[(3R)-3-[4-(3-pyridinyl)-1H-imidazol-1-yl]butyl]-1,2-hydrazinedicarboxylate (32) in methanol was added 6N hydrochloric acid. The reaction was heated to 50° C. and stirred 18 h.

Sources & evidence

ORD record
ord-83d2adaa199642839ac5a204d9972d84
Source dataset
uspto-grants-2002_06
Patent number
US06403776B1

Reaction notes

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