HRID2186446

反应详情

EQUATION

反应方程式

HRID 2186446 的结构方程式

CONDITIONS

反应条件

温度
80 °C

PROCEDURE

实验过程

A mixture of 7-bromo-4-methoxy-2-methylsulfanylbenzooxazole (10.0 g) and morpholine (6.6 ml) were heated at 80° C. for 18 hours. Purification by chromatography on silica eluting with 20-100% ethyl acetate in heptane afforded the title compound as an off-white solid (11.6 g).

WORKUP

后处理

  1. customPurification by chromatography on silica eluting with 20-100% ethyl acetate in heptane