HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 7-Bromo-4-methoxy-2-(piperidin-1-yl)-benzooxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 7-Bromo-4-methoxy-2-methylsulfanylbenzooxazole | HCID 22456651 | — |
| Product | 7-Bromo-4-methoxy-2-(piperidin-1-yl)-benzooxazole | HCID 22456660 | — |
Reaction Steps
Starting from 7-bromo-4-methoxy-2-methylsulfanylbenzooxazole (10.0 g) and piperidine (3.8 ml). Purification by chromatography on silica eluting with 30-100% ethyl acetate in hexane afforded the title compound as an off-white solid (10.7 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06403791B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-4131b1fea08641af91a9ebe9526d070e |
| Source note | uspto-grants-2002_06 |