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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2186450Generated: October 31, 2026

7-Bromo-4-methoxy-2-(piperidin-1-yl)-benzooxazole → 7-Bromo-2-(piperidin-1-yl)-benzooxazol-4-ol

https://huagongshe.com/reaction/2186450

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Bromo-4-methoxy-2-(piperidin-1-yl)-benzooxazoleHCID 22456660—
SolventDiethyl EtherHCID 3283—
Product7-Bromo-2-(piperidin-1-yl)-benzooxazol-4-olHCID 2245664986.8%

Reaction Steps

Starting from 7-bromo-4-methoxy-2-(piperidin-1-yl)-benzooxazole (9.0 g). Trituration in diethyl ether afforded the title compound as a pale brown solid (7.46 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06403791B1
Source datasetuspto-grants-2002_06
ORD IDord-1fb576c0dcc84b5f8dcdcb811f895419
Source noteuspto-grants-2002_06