反应详情

Starting from 4-difluoromethoxy-2-ethylbenzooxazole-7-carboxylic acid 4-nitro-phenyl ester (100 mg) and 4-bromo-2-methyl-2H-pyrazol-3-ylamine (93 mg). Purification by column chromatography on silica eluting with 1-5% methanol in dichloromethane afforded, after trituration with diethyl ether, the title compound as a white solid (7 mg).

1. customPurification by column chromatography on silica eluting with 1-5% methanol in dichloromethane
2. customafforded