反应详情

In a 200 ml autoclave were charged 4.50 g (20.9 mmol) of ethyl (R)-4-azido-3-acetoxybutyrate, 0.02 g of 5% Pd—C, and 5 ml of ethyl acetate, and the mixture was stirred at room temperature under a hydrogen pressure of 1000 KPa overnight. The catalyst was removed for concentration to give 3.20 g (81%) of the title compound.

1. customThe catalyst was removed for concentration