Tetrahydrothiophene → HCID 86584190, compound

HRID 2186646Notes

Reaction equation

HRID 2186646 reaction equation
[S:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:6][CH:7](Br)[C:8](=[O:10])[CH3:9]>CC(C)=O>[Br-:6].[Br-:6].[O:10]=[C:8]([CH2:7][S+:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)[CH2:9][S+:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 1127TetrahydrothiopheneHCID 5401181,1-Dibromopropanone

Product 1

HCID 86584190HCID 86584190, compoundYield 66.9%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Into a four-necked flask were charged 4.7 parts of tetrahydrothiophene, 5.2 parts of dibromoacetone and 47.1 parts of acetone, and they were stirred at room temperature for 24 hours. The deposited crystals were filtered and washed with acetone. The obtained filter cake was combined with ether and the mixture was stirred. After filtration, the filter cake was washed with ether and dried to give 6.4 parts of 1,1′-(2-oxo-1,3-propanediyl)bis(tetrahydrothiophenium) dibromide. Yield: 66.9%.

Workup

  1. filtrationThe deposited crystals were filtered
  2. washwashed with acetone
  3. filtrationThe obtained filter cake
  4. stirringthe mixture was stirred
  5. filtrationAfter filtration
  6. washthe filter cake was washed with ether
  7. customdried

Sources & evidence

ORD record
ord-2f7f8d6b8e58403a86bbfad8a8715b4e
Source dataset
uspto-grants-2002_06
Patent number
US06406830B2

Reaction notes

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