Potassium Hydroxide → HCID 136383543, compound

Participants

Reaction Steps

Process c) 3.67 g (0.0125 mol) of S-[2-(3-methoxyimino-3H-benzofuran-2-ylideneaminooxy)-ethyl] thioacetate in 40 ml of methanol are heated under reflux with 12.5 ml of 2N aqueous potassium hydroxide solution for 15 minutes. The solvent is then distilled off under reduced pressure and the residue is admixed with 2N aqueous hydrochloric acid. The mixture is extracted with diethyl ether, the organic phase is dried over sodium sulphate and the solvent is distilled off under reduced pressure. The residue is stirred with diethyl ether, giving 0.78 g (24.7% of theory) of (5,6-dihydro-[1,4,2]oxathiazin-3-yl)-(2-hydroxyphenyl)-methanone O-methyloxime.

Provenance & Evidence