1-Naphthaldehyde → HCID 69686696, compound

HRID 2186890Notes

Reaction equation

N[C:2]1[CH:21]=[CH:20][C:5]2[N:6]([CH3:19])[C:7]([CH2:9][CH2:10][C:11]3[CH:16]=[CH:15][C:14]([C:17]#[N:18])=[CH:13][CH:12]=3)=[N:8][C:4]=2[CH:3]=1.[C:22]1([CH:32]=O)[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH:25]=[CH:24][CH:23]=1>>[C:17]([C:14]1[CH:15]=[CH:16][C:11]([CH2:10][CH2:9][C:7]2[N:6]([CH3:19])[C:5]3[CH:20]=[CH:21][C:2]([CH2:32][C:22]4[C:31]5[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=5)[CH:25]=[CH:24][CH:23]=4)=[CH:3][C:4]=3[N:8]=2)=[CH:12][CH:13]=1)#[N:18]

Participants

Reactant 2

HCID 61951-Naphthaldehyde

HCID 18763022HCID 18763022, compound

Product 1

HCID 69686696HCID 69686696, compound

Procedure

5-Amino-2-[2-(4-cyanophenyl)-ethyl]-1-methyl-benzimidazole (35.5 g, 129.0 mmol) (obtainable according to Example 1, Step c) and 18.2 ml of naphthaline-1-carbaldehyde are reacted by reductive amination according to Example 5, Step a.

Sources & evidence

ORD record: ord-7269c37f98ee4449988af4446ecd6d9c
Source dataset: uspto-grants-2002_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06407130B1

Reaction notes

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