反应详情

温度

130 °C

A Teflon tube containing a mixture of 0.16 g (2.8 mmoles) of methyl isocyanate, 0.27 g (3.8 mmoles) of ethyl vinyl ether and 2 ml of toluene was sealed and introduced into a high-pressure reactor and the mixture was heated at 130° C. under a pressure of 8000 atmospheres for 20 hours. The reaction mixture taken out was evaporated and then purified by distillation under reduced pressure to obtain 1-methyl-4-ethoxy-2-azetidinone in a yield of 16% of the theoretical value.

1. additionA Teflon tube containing
2. customwas sealed
3. additionintroduced into a high-pressure reactor
4. customThe reaction mixture taken out was evaporated
5. distillationpurified by distillation under reduced pressure