5-Amino-2-chloropyridine → 6-methoxy-N-methylpyridin-3-amine

HRID 2187220Notes

Reaction equation

HRID 2187220 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([O:8][CH3:9])=[N:6][CH:7]=1.N[C:11]1C=CC(Cl)=NC=1>>[CH3:9][O:8][C:5]1[CH:4]=[CH:3][C:2]([NH:1][CH3:11])=[CH:7][N:6]=1

Participants

3

Reactant 2

HCID 793055-Amino-2-chloropyridineHCID 811216-Methoxy-3-pyridinylamine

Product 1

HCID 110734966-methoxy-N-methylpyridin-3-amine

Procedure

The reaction procedure of Reference Example 24 was repeated except that 5-amino-2-methoxypyridine was used in lieu of 5-amino-2-chloropyridine to give the title compound as a yellow oil.

Workup

  1. customThe reaction procedure of Reference Example 24

Sources & evidence

ORD record
ord-7951f5501b774e538e0e41a86f4c15a7
Source dataset
uspto-grants-2002_06
Patent number
US06407248B1

Reaction notes

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