Phosphorus trichloride → HCID 11161344, compound

Participants

Reaction Steps

From the literature, processes are already known for the production of 10-chloro-phenoxaphosphines. Freedman et al describes in J. Organ. Chem. 1961, Vol 26, 284 the conversion of p-tolyl ether with phosphorus trichloride and aluminum trichloride. After the aqueous processing, the reaction product was identified as 2,8-dimethyl-phenoxaphosphinic acid. The 2,8-dimethyl-phenoxaphosphinc acid can be converted analogously to the teaching of Hellwinkel and Krapp in Chem. Ber. 1978, Vol 111, 13 for dibenzophosphoric acid by reaction with phosphorus oxychloride at 200° C. and subsequent reaction with red phosphorus at 180° C. to form 10-chloro-2,8-dimethylphenoxaphosphine. The synthesis from ether is thus a three-stage synthesis and the total yield is 59.6% over all stages. Thus, an economical production of the compound is not possible.

Provenance & Evidence