HCID 18669803, compound → HCID 18475148, compound

HRID 2187307Notes

Reaction equation

HRID 2187307 reaction equation
[CH3:1][CH:2]([CH3:4])[O-:3].[Li+:5].[CH3:6][CH:7]([CH3:9])[O-:8].[CH3:10][Al+:11][CH3:12]>C(OCC)C>[CH3:1][CH:2]([CH3:4])[O-:3].[CH3:10][Al+:11][CH3:12].[Li+:5].[CH3:6][CH:7]([CH3:9])[O-:8]

Participants

4

Reactant 2

HCID 18669803HCID 18669803, compoundHCID 23673350Lithium propan-2-olate

Product 1

HCID 18475148HCID 18475148, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

3.55 g (53.8 mmol) of lithium isopropoxide was added to 6.25 g (53.8 mmol) of dimethylaluminum isopropoxide dissolved in diethyl ether and stirred for a day. The resulting mixture was distilled under a reduced pressure to remove the solvent and the resulting solid residue was sublimed under a vacuum at 110° C. to obtain 8.98 g (49.3 mmol; 92% yield) of the title compound in the form of a white solid.

Workup

  1. distillationThe resulting mixture was distilled under a reduced pressure
  2. customto remove the solvent
  3. customwas sublimed under a vacuum at 110° C.

Sources & evidence

ORD record
ord-c11d12f1d1d44471b15f0916b12a6759
Source dataset
uspto-grants-2002_06
Patent number
US06409830B1

Reaction notes

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