HCID 11024302, compound → HCID 11108888, compound

HRID 2187341Notes

Reaction equation

HRID 2187341 reaction equation
C([NH:5][S:6]([C:9]1[CH:14]=[C:13]([N:15]=[CH:16][N:17]([CH3:19])[CH3:18])[CH:12]=[CH:11][C:10]=1[C:20]([O:22][CH3:23])=[O:21])(=[O:8])=[O:7])(C)(C)C>FC(F)(F)C(O)=O>[CH3:18][N:17]([CH3:19])[CH:16]=[N:15][C:13]1[CH:12]=[CH:11][C:10]([C:20]([O:22][CH3:23])=[O:21])=[C:9]([S:6]([NH2:5])(=[O:8])=[O:7])[CH:14]=1

Participants

3

Reactant 1

HCID 11024302HCID 11024302, compound

Product 1

HCID 11108888HCID 11108888, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

A mixture of 2.13 g of N-tert-butyl-2-methoxycarbonyl-5-(2-dimethylamino-1-azaethenyl)benzenesulfonamide and 20 ml of trifluoroacetic acid is stirred at room temperature until the reaction has ended. The volatile components are then distilled off under reduced pressure. The residue is washed with diisopropyl ether and then with NaHCO3 solution. This affords 1.77 g of the desired compound.

Workup

  1. distillationThe volatile components are then distilled off under reduced pressure
  2. washThe residue is washed with diisopropyl ether

Sources & evidence

ORD record
ord-a92d2749bd8d47ceb9f13ad3ea17c71d
Source dataset
uspto-grants-2002_06
Patent number
US06410482B1

Reaction notes

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