Sodium Hydroxide → HCID 18475415, compound

Participants

Reaction Steps

To a solution of 1-10a (0.15 g, 0.353 mmol) in ethanol (1 mL) was added NaOH (0.39 rnL of 1N solution in water, 0.39 mmol). After 30 minutes, the mixture was concentrated, and the residue chromatographed on silica gel (20:10:1:1 to 10:10:1:1 ethyl acetate/ethanol/NH4OH/water) to give 1-11a as a white solid.

Provenance & Evidence