HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-benzyloxy-N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide → HCID 59191193, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-benzyloxy-N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 17854215 | — |
| Reactant | 2-Ethyl-4-(trifluoromethyl)-5-thiazolemethanol | HCID 17854446 | — |
| Product | HCID 59191193 | HCID 59191193 | 22.6% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 142 using 2-ethyl-5-hydroxymethyl-4-trifluoromethylthiazole (0.63 g) and 5-benzyloxy-N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (1.2 g) as starting materials, 5-benzyloxy-N-[(2-ethyl-4-trifluoromethylthiazol-5-yl)methyl]-N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.4 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-31c8fac5d65d471fb20c2d18c3ae72f2 |
| Source note | uspto-grants-2012_06 |