Tolylboronic acid → HCID 12659171, compound

HRID 2187636Notes

Reaction equation

HRID 2187636 reaction equation
Br[C:2]1[S:3][C:4]2[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:5]=2[CH:6]=1.[CH3:12][C:13]1[CH:18]=[CH:17][C:16](B(O)O)=[CH:15][CH:14]=1>C(OCC)(=O)C>[Cl:11][C:8]1[CH:9]=[CH:10][C:4]2[S:3][C:2]([C:16]3[CH:17]=[CH:18][C:13]([CH3:12])=[CH:14][CH:15]=3)=[CH:6][C:5]=2[CH:7]=1

Participants

4

Reactant 2

HCID 79799Tolylboronic acidHCID 184763002-Bromo-5-chloro-1-benzothiophene

Product 1

HCID 12659171HCID 12659171, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The compound was prepared in the same manner as described in Preparation 48, Step B, from 2.06 g (8.32 mmol) 2-bromo-5-chlorobenzothiophene and 2.44 g (17.95 mmol) 4-methylbenzeneboronic acid and isolated by crystallization from ethyl acetate.

Workup

  1. customThe compound was prepared in the same manner

Sources & evidence

ORD record
ord-c3bd66f4ea874e078ff07dc2e86bf7b6
Source dataset
uspto-grants-2002_06
Patent number
US06410562B1

Reaction notes

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