Hydrochloric Acid → HCID 178499561, compound

Participants

Reaction Steps

A solution of 4-imidazoleacetic acid hydrochloride (4.00 g, 24.6 mmol) in MeOH (100 mL) was saturated with HCl (g). Trimethyl orthoformate (10 mL, 91 mmol) was added and the mixture was stood at ambient temperature for 18 hrs, then concentrated to dryness in vacuo to afford the titled ester as a white solid.

Provenance & Evidence