Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218809Generated: October 29, 2026

HCID 17854370, compound → HCID 59597422, compound

https://huagongshe.com/reaction/218809

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 17854370HCID 17854370—
ReactantThiazole, 5-(chloromethyl)-2-ethyl-4-methyl-HCID 17854442—
ProductHCID 59597422HCID 5959742246.8%

Reaction Steps

By the reaction and treatment in the same manner as in Example 132 using 5-benzyloxy-N-(5-methylpyridin-2-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (1.43 g) and 5-chloromethyl-2-ethyl-4-methylthiazole (0.68 g) as starting materials, 5-benzyloxy-N-[(2-ethyl-4-methylthiazol-5-yl)methyl]-N-(5-methylpyridin-2-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.92 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-8dd0f3d0f59543ce870291558af76773
Source noteuspto-grants-2012_06