HCID 54418911, compound → gamma-(1-Naphthyl)butyric acid

HRID 2188205Notes

Reaction equation

HRID 2188205 reaction equation
[C:1]1([CH2:11][CH:12]=[CH:13][C:14]([OH:16])=[O:15])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1>C(O)C.[Pd]>[C:1]1([CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 1

HCID 54418911HCID 54418911, compound

Product 1

HCID 13077gamma-(1-Naphthyl)butyric acidYield 89.8%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

To a solution of 4-(1-naphthyl)butenoic acid (3.96 g) in ethyl alcohol (45 cm3) was added palladium on carbon (10%, 400 mg). The mixture was stirred under hydrogen (approx. 2 atm) for 3 h. The catalyst was then removed by filtration through a pad of Dicalite® and the solvent was removed under reduced pressure to yield the title compound (3.59 g).

Workup

  1. customThe catalyst was then removed by filtration through a pad of Dicalite®
  2. customthe solvent was removed under reduced pressure

Sources & evidence

ORD record
ord-687293b14657471c9b0be82c989f2faa
Source dataset
uspto-grants-2002_06
Patent number
US06410592B1

Reaction notes

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