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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2189008Generated: October 27, 2026

1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)- → Pyrrolidine-1,2-dicarboxylic acid

https://huagongshe.com/reaction/2189008

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-HCID 85083—
ReactantHCID 178469704HCID 178469704—
ProductPyrrolidine-1,2-dicarboxylic acidHCID 14794868321.1%

Reaction Steps

The product of Example 5, step b) was treated by the same method as that described in Example 10, step a) except N-Boc-L-Proline (12.6 g, 5.87 mmol) was used to give the sub-title compound as a pale yellow solid (3.0 g, 60%). MS: ESI (positive): 791 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324210B2
Source datasetuspto-grants-2012_12
ORD IDord-c8ba5ea9e3204ee78dc2a52a6b18696e
Source noteuspto-grants-2012_12