反应详情

Add 1.3 g of palladium on activated carbon (10%) to 13 g (61.6 mmol) of 3-nitrophenoxyacetic acid methyl ester in 150 ml of methanol under argon. Stir the mixture at RT under a hydrogen atmosphere (standard pressure) for 18 h. Filter the catalyst off through kieselguhr and concentrate the filtrate under reduced pressure. After drying under high vacuum, 10.7 g (95.9% of theory) of the target compound are obtained.

1. filtrationFilter the catalyst off through kieselguhr
2. concentrationconcentrate the filtrate under reduced pressure
3. customAfter drying under high vacuum, 10.7 g (95.9% of theory) of the target compound
4. customare obtained