Potassium Carbonate → HCID 58280122, compound

Participants

Reaction Steps

Stir 1000 mg (2.97 mmol) of 4-chloro-5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidine, 1296 mg (11.9 mmol) of 3-aminophenol and 615.6 mg (4.45 mmol) of potassium carbonate in 10 ml of DMF at 80° C. for 8 h. After cooling, concentrate under reduced pressure and take up the residue in water. Filter off the precipitated solid, wash the filter residue repeatedly with water and dry the solid at 50° C. under high vacuum. 1195 mg (98.3% of theory) of the target compound are obtained as a brownish solid.

Provenance & Evidence