Sodium Hydroxide → HCID 67160427, compound

Participants

Reaction Steps

Dissolve 150 mg (0.322 mmol) of 3-(3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)propanoic acid in 5 ml of THF and add 0.322 ml of 1N sodium hydroxide solution. Stir the mixture at RT for 1 h, then concentrate under reduced pressure and dry the residue under high vacuum overnight. 155.7 mg (99.1% of theory) of the target product are obtained as a colourless solid.

Provenance & Evidence