N-benzylaminosulfonamide → Benzylsulfamide potassium salt

HRID 2189129Notes

Reaction equation

HRID 2189129 reaction equation
[CH2:1]([NH:8][S:9]([NH2:12])(=[O:11])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.CC([O-])(C)C.[K+:18]>>[K+:18].[CH2:1]([NH:8][S:9]([NH-:12])(=[O:11])=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 12354987N-benzylaminosulfonamideHCID 23665647Potassium tert-butoxide

Product 1

HCID 21041359Benzylsulfamide potassium saltYield 100.6%

Procedure

To a solution of benzylsulfamide (17.98 g) in McOH (300 mL) was carefully added potassium tert-butylate (10.8 g). The mixture was stirred at rt for 15 min before the solvent was evaporated. The remaining residue was dried under HV to give benzylsulfamide potassium salt as an off-white powder (21.73 g).

Workup

  1. customwas evaporated
  2. customThe remaining residue was dried under HV

Sources & evidence

ORD record
ord-5d1afc6e2d174f638edd86682471e518
Source dataset
uspto-grants-2012_12
Patent number
US08324232B2

Reaction notes

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