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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2189226Generated: November 4, 2026

HCID 136068452, compound → HCID 135921476, compound

https://huagongshe.com/reaction/2189226

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 136068452HCID 136068452—
ReactantHCID 136398357HCID 136398357—
ProductHCID 135921476HCID 135921476—

Reaction Steps

The title compound was prepared using methods analogous to those described in Synthesis 59 and 60, replacing (S)-tert-butyl 3-(6-bromo-2-(2-hydroxyphenyl)quinazolin-4-ylamino)pyrrolidine-1-carboxylate with (S)-tert-butyl 3-(7-bromo-2-(5-fluoro-2-hydroxyphenyl)quinazolin-4-ylamino)pyrrolidine-1-carboxylate in Synthesis 59-A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324226B2
Source datasetuspto-grants-2012_12
ORD IDord-0a376c596f5a4a809804bca170bb8181
Source noteuspto-grants-2012_12