HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 135921487, compound → HCID 135921488, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 135921487 | HCID 135921487 | — |
| Reactant | HCID 136068452 | HCID 136068452 | — |
| Product | HCID 135921488 | HCID 135921488 | — |
Reaction Steps
The title compound was synthesised using methods analogous to those described in Synthesis 60 and 85-A, with (S)-tert-butyl 3-(2-(2-hydroxyphenyl)-6-(3-hydroxyprop-1-ynyl)quinazolin-4-ylamino)pyrrolidine-1-carboxylate replaced with (S,E)-2-(7-(3-methoxyprop-1-enyl)-4-(pyrrolidin-3-ylamino)quinazolin-2-yl)phenol in Synthesis 60.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324226B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-a762ccd69f854db09bd0fcaa84a7f9b5 |
| Source note | uspto-grants-2012_12 |