tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate → 1-[7-cyclopentyl-2-(4-piperazin-1-yl-phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-ethanone

Participants

Reaction Steps

1-[7-cyclopentyl-2-(4-piperazin-1-yl-phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-ethanone is prepared from 1-(2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-ethanone and 4-(4-Aminophenyl)-piperazine-1-carboxylic acid tert-butyl ester using a method similar to that for the preparation of Example 202. [M+H+] 405.2.

Provenance & Evidence