HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate → (7-Cyclopentyl-5-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-(5-piperazin-1-yl-pyridin-2-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | HCID 11737525 | — |
| Reactant | 2-Chloro-7-cyclopentyl-5-isopropyl-7H-pyrrolo[2,3-d]pyrimidine | HCID 84819805 | — |
| Product | (7-Cyclopentyl-5-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-(5-piperazin-1-yl-pyridin-2-yl)-amine | HCID 58015852 | — |
Reaction Steps
(7-Cyclopentyl-5-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-(5-piperazin-1-yl-pyridin-2-yl)-amine is prepared from 2-Chloro-7-cyclopentyl-5-isopropyl-7H-pyrrolo[2,3-d]pyrimidine and 4-(6-Amino-pyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester using a method similar to that for the preparation of Example 202. [MH+] 406.21
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324225B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-a26a4a0e130946bfa2df9738bacb9039 |
| Source note | uspto-grants-2012_12 |