Hydroxylamine → HCID 11523623, compound

HRID 218932Notes

Reaction equation

HRID 218932 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[CH:18]=[N:17][CH:16]=[CH:15][C:11]=1[C:12](O)=[O:13].[NH2:19][OH:20]>>[F:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[CH:18]=[N:17][CH:16]=[CH:15][C:11]=1[C:12]([NH:19][OH:20])=[O:13]

Participants

3

Reactant 2

HCID 787HydroxylamineHCID 590267913-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid2×

Product 1

HCID 11523623HCID 11523623, compound

Procedure

3-[(2-fluoro-4-iodophenyl)amino]-N-hydroxyisonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.31 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.6 mmol of hydroxylamine. LC/MS [7.37 min; 374 (M+1)]

Workup

  1. customLC/MS [7.37 min; 374 (M+1)]

Sources & evidence

ORD record
ord-ec1236815fdc4bddb2b5c8ae26ded4d4
Source dataset
uspto-grants-2012_06
Patent number
US08198457B2

Reaction notes

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