HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 44251385, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68968247 | HCID 68968247 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 44251385 | HCID 44251385 | 90% |
Reaction Steps
The tert-butyl-3-(methyl(6-(2-methylpyridine-3-yloxy)pyridine-3-yl)carbamoyl)-1H-indole-1-carboxylate (40 mg, 0.087 mmol) was added to a mixed solution of dichloromethane (1 ml) and TFA (1 ml), and the mixture was stirred at room temperature for 1 hour. Subsequently, the product was filtered, washed, and dried to yield a target compound as a white solid (28 mg, 90%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324246B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-ea81bc2a180547b68c05949e97f83314 |
| Source note | uspto-grants-2012_12 |