Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2189472Generated: October 30, 2026

Trifluoroacetic acid → HCID 44251385, compound

https://huagongshe.com/reaction/2189472

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68968247HCID 68968247—
SolventDichloromethaneHCID 6344—
ProductHCID 44251385HCID 4425138590%

Reaction Steps

The tert-butyl-3-(methyl(6-(2-methylpyridine-3-yloxy)pyridine-3-yl)carbamoyl)-1H-indole-1-carboxylate (40 mg, 0.087 mmol) was added to a mixed solution of dichloromethane (1 ml) and TFA (1 ml), and the mixture was stirred at room temperature for 1 hour. Subsequently, the product was filtered, washed, and dried to yield a target compound as a white solid (28 mg, 90%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324246B2
Source datasetuspto-grants-2012_12
ORD IDord-ea81bc2a180547b68c05949e97f83314
Source noteuspto-grants-2012_12