反应详情

温度

80 °C

A mixture of pyridine-2,5-dicarboxylic acid 5-methyl ester (150 mg, 0.828 mmol) and thionyl chloride (1 mL) was heated at 80° C. for 5 h. The thionyl chloride was evaporated under reduced pressure, the residue was dried in high vacuum and used crude for the next reaction.

1. customThe thionyl chloride was evaporated under reduced pressure
2. customthe residue was dried in high vacuum
3. customfor the next reaction