HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 5-(3-chloro-4-fluorophenyl)-4-(3-cyano-5-fluorophenyl)furan-2-carboxylate → Ethyl 5-(3-chlorophenyl)-4-(3-cyano-5-fluorophenyl)furan-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 5-(3-chloro-4-fluorophenyl)-4-(3-cyano-5-fluorophenyl)furan-2-carboxylate | HCID 58064770 | — |
| Reactant | Ethyl 4-bromo-5-(3-chlorophenyl)furan-2-carboxylate | HCID 58064772 | — |
| Product | Ethyl 5-(3-chlorophenyl)-4-(3-cyano-5-fluorophenyl)furan-2-carboxylate | HCID 58064792 | — |
Reaction Steps
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 15A starting with the compound from Example 5A. 111 mg (52% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324268B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-db6aa10679fb4b0786ec0dbb7c804b78 |
| Source note | uspto-grants-2012_12 |