HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 5-(3-chloro-4-fluorophenyl)-4-(3-cyano-5-fluorophenyl)furan-2-carboxylate → Ethyl 4-(3-cyano-5-fluorophenyl)-5-(3-cyanophenyl)furan-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 5-(3-chloro-4-fluorophenyl)-4-(3-cyano-5-fluorophenyl)furan-2-carboxylate | HCID 58064770 | — |
| Reactant | Ethyl 4-bromo-5-(3-cyanophenyl)furan-2-carboxylate | HCID 58064801 | — |
| Product | Ethyl 4-(3-cyano-5-fluorophenyl)-5-(3-cyanophenyl)furan-2-carboxylate | HCID 58064789 | — |
Reaction Steps
The synthesis of the title compound takes place in analogy to the synthesis of the compound from Example 15A starting with the compound from Example 8A. 190 mg (56% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324268B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-06389bf1d6e24b28a7210b5b6ff189a1 |
| Source note | uspto-grants-2012_12 |