HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-{[4-Bromo-5-(3-chlorophenyl)furan-2-yl]carbonyl}piperazin-2-one → 4-{[5-Bromo-4-(3-chlorophenyl)furan-2-yl]carbonyl}piperazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-{[4-Bromo-5-(3-chlorophenyl)furan-2-yl]carbonyl}piperazin-2-one | HCID 58064764 | — |
| Reactant | 5-Bromo-4-(3-chlorophenyl)furan-2-carboxylic acid | HCID 58064802 | — |
| Product | 4-{[5-Bromo-4-(3-chlorophenyl)furan-2-yl]carbonyl}piperazin-2-one | HCID 58064780 | — |
Reaction Steps
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 27A starting with the compound from Example 22A. 48.0 mg (79% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324268B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-c968acfb4bae494e8655befc1d8781c9 |
| Source note | uspto-grants-2012_12 |