HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[3-(3-Chloro-5-fluorophenyl)-5-(1,3-thiazolidin-3-ylcarbonyl)furan-2-yl]benzenecarbonitrile → [5-(3-Chloro-4-fluorophenyl)-4-(3-chloro-5-fluorophenyl)furan-2-yl](1,3-thiazolidin-3-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[3-(3-Chloro-5-fluorophenyl)-5-(1,3-thiazolidin-3-ylcarbonyl)furan-2-yl]benzenecarbonitrile | HCID 46832300 | — |
| Reactant | 5-(3-Chloro-4-fluorophenyl)-4-(3-chloro-5-fluorophenyl)furan-2-carboxylic acid | HCID 58064796 | — |
| Product | [5-(3-Chloro-4-fluorophenyl)-4-(3-chloro-5-fluorophenyl)furan-2-yl](1,3-thiazolidin-3-yl)methanone | HCID 46832583 | — |
Reaction Steps
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 1 starting with the compound from Example 21A. 144 mg (48% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324268B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-fa1ac8fe87ea48ca9d4c3e0baf7b36ed |
| Source note | uspto-grants-2012_12 |