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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2190141Generated: October 30, 2026

4-(3-Chloro-5-fluorophenyl)-5-(3-cyanophenyl)furan-2-carboxylic acid → HCID 46832880, compound

https://huagongshe.com/reaction/2190141

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Chloro-5-fluorophenyl)-5-(3-cyanophenyl)furan-2-carboxylic acidHCID 58064798—
Reactant4-{[4-(3-Chlorophenyl)-5-(4-fluorophenyl)furan-2-yl]carbonyl}piperazin-2-oneHCID 58064800—
ProductHCID 46832880HCID 46832880—

Reaction Steps

The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 6 starting with the compound from Example 20A and the compound from Example 35A. 1.1 equivalents of the compound from Example 35A are used. 42.0 mg (70% of theory) of the title compound are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324268B2
Source datasetuspto-grants-2012_12
ORD IDord-4bc2efda5e0e4918bca35a2688892892
Source noteuspto-grants-2012_12